Droplette

Developed by two MIT scientists, our patented system unlocks the full potential of cutting-edge skincare ingredients. MADHAVI GAVINI & RATHI SRINIVAS It started with a simple question: What if we could design a way to deliver clinically-effective ingredients directly where they’ll have the greatest impact? For our founders, Madhavi Gavini and Rathi Srinivas, this wasn’t just a thought experiment—it was a mission. As MIT-trained scientists, their research focused on solving complex medical challenges, including epidermolysis bullosa (EB), a rare genetic condition that causes extremely fragile skin. For patients with EB, even the gentlest creams offered little relief and were often too painful to apply. Determined to find a better way, they engineered a breakthrough delivery system—transforming potent ingredients into a barrier-penetrating mist—that achieves unprecedented efficacy without any downsides. What began as a treatment for a genetic disorder redefined what’s possible in skincare—unlocking powerful results, with none of the trade-offs. Your skin is an incredibly effective protective barrier—so effective that research shows >90% of traditional skincare products like serums and moisturizers can't penetrate beyond the outermost layer. This surface-level limitation means most active ingredients never reach the deeper skin layers where they're actually needed to create visible changes. Droplette uses advanced transdermal technology to solve this fundamental problem. Our proprietary delivery system works like a microscopic key, safely opening temporary pathways in your skin's barrier to deliver proven active ingredients directly into the deeper layers—without needles or discomfort DERMATOLOGIST APPROVED FOR VISIBLE RESULTS In just one minute a day, our targeted serums—infused with pharmaceutical-grade actives—transform skin on a cellular level. Droplette's cutting-edge technology and proven efficacy are supported by rigorous scientific research and peer-reviewed publications. It is the first skincare delivery system powered by technology validated by NASA and the National Institutes of Health. In collaboration with leading experts and advisors, we partner with the Walter Reed Army Institute to deploy Droplette in treating blast wounds on the battlefield. Droplette - A Fluid Dynamics Driven Platform for Transdermal and Intra-Cellular Delivery of Large Molecules, Mahmood et al. FASEB 2018. Transdermal Delivery of High Molecular Weight Antibiotics to Deep Tissue Infections via Droplette Micromist Technology Device (DMTD), Pulakat et al, Pharmaceutics 2022. Droplette: A Platform Technology to Directly Deliver Nucleic Acid Therapeutics and Other Molecules into Cells and Deep into Tissue Without Transfection Reagents, Biomedical Engineering Technologies 2022. Discover our revolutionary skincare system, where potent serums are amplified by our patented delivery technology—for results without compromise.

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